Ruth Winter, M.S.
See book keywords and concepts |  DERMATAN SULFATE • chondroitin sulfate. Chondroitin Sulfuric Acid. Occurs in both skeletal and soft connective tissue. It is abundant in skin, arterial walls, and heart valves. DERMATITIS • Inflammation of the skin.
DERMIS • The lower layer of skin, overlying subcutaneous fat and composed of blood vessels, lymph sacs, sensory nerve endings, hair follicles, and oil and sweat glands.
DERMOLECT1NE • New ingredient that at this writing was being developed. It is from potatoes and acts similar to a hormone. It is a cellular growth promoter. |
Textbook of Natural Medicine 2nd Edition Volume 1Michael T. Murray, ND
See book keywords and concepts | | In addition to sulfur playing a critical role in the manufacture of glycosaminoglycans (GAGs) like chondroitin sulfate and keratan sulfate, sulfur has been shown to inhibit the various enzymes which lead to cartilage destruction in osteoarthritis (e.g. collagenase, elastases, and hyaluronidase).16,19
Because one of the primary effects of glucosamine sulfate is to promote the manufacture of GAGs, a lack of the sulfur moiety may mean less GAG synthesis when glucosamine HCI is used. |
Textbook of Natural Medicine 2nd Edition Volume 2Michael T. Murray, ND
See book keywords and concepts | | In addition to vitamin C and CoQ10, a mixture of highly purified bovine-derived glycosaminoglycans naturally present in the aorta, including dermatan sulfate, heparan sulfate, hyaluronic acid, chondroitin sulfate, and related hexosaminoglycans, is also of benefit in preventing re-perfusion injury and restoring proper structure, integrity, and function of the coronary vascular endothelium.13 The dosage of purified aortic GAGs is 100 mg daily. |
Sheldon Saul Hendler
See book keywords and concepts |  See discussion of hyaluronic acid, this section, for news of a drug that combines chondroitin sulfate with hyaluronic acid.)
Deaner (DMAE)
(Life Shortener?)
"Deaner" and "Deanol" were the registered names of prescription drugs that contain dimethylaminoethanol (DMAE), thought to be a precursor of acetylcholine (see discussion of choline elsewhere in this book). Like choline, DMAE has been used to treat various disorders of the nervous system. It appears to have a beneficial role in the treatment of tardive dyskinesia and Huntington's chorea. |
Jack Challem
See book keywords and concepts |  Fifty-two percent of patients with mild or moderate osteoarthritis of the knee benefited from symptom reductions of 25 percent or more after taking the dietary supplements. In contrast, only about half that number of patients improved with the placebo.
Perhaps the most significant recent study was directed by Jean-Yves Reginster, M.D., of the University of Liege, Belgium. He and his fellow Belgian, Italian, and British researchers used digitized X rays to carefully measure the rate of knee cartilage damage in 106 patients with osteoarthritis. |
Janet Zand, LAc, OMD, Allan N. Spreed, MD, CNC, James B. LaValle, RPh, ND
See book keywords and concepts |  Take 500 milligrams of glucosamine sulfate or hydrochloride three times daily (four times daily if you weigh over 200 pounds) for three to four months.
¦ chondroitin sulfate enhances the activity of glucosamine. Take 500 milligrams twice daily.
¦ Inositol is required for proper muscle function. This is an important supplement to include if the bursitis is accompanied by neuritis. Take 500 milligrams three times daily for one to two weeks. Inositol works quickly. Relief should be apparent after one week.
¦ Proteolytic enzymes work to decrease inflammation and help relieve pain. | | Take 500 milligrams of glucosamine sulfate or glucosamine hydrochloride (HCI) two or three times daily and 500 milligrams of chondroitin sulfate twice a day.
¦ Genistein is a phytoestrogen derived from soybeans or red clover. Plant estrogens have much milder effects than human estrogens do. However, it has been observed that Japanese women, who eat a lot of soy foods, have relatively high levels of phytoestrogens in their blood, and also have fewer menopausal symptoms than their Western counterparts. | | A multivitamin and mineral supplement, plus supplemental glucosamine sulfate, chondroitin sulfate, and/ or evening primrose or flaxseed oil. In addition, make certain that your calcium intake equals approximately 1,200 milligrams daily, and your magnesium intake 600 to 800 milligrams daily.
¦ If you are interested in exploring hormone replacement therapy, discuss with your doctor the possible use of natural hormone replacement using triple-estrogen, or "tri-est," and natural progesterone. These are available from compounding pharmacists. | | Take 500 milligrams of glucosamine sulfate and 350 milligrams of chondroitin sulfate three times daily. If you weigh more than 200 pounds, take the same amount four times daily.
¦ Green-foods supplements, available in health-food stores, are high in trace minerals essential to the laying down of bone. Take a green-foods supplement twice a day, as directed on the product label.
HERBAL TREATMENT
¦ Horsetail is high in silica, which is important for the proper formation of bone and connective tissue. Take 500 milligrams twice a day for three months. |
Gale Maleskey
See book keywords and concepts |  Apart from their absorption rates, another difference between glucosamine and chondroitin sulfate may lie in how they go about the business of saving cartilage from destruction. Whereas glucosamine may help with the rebuilding of cartilage to keep up with its breakdown, chondroitin may actually decrease the breakdown, says Dr. Das, swimming, and biking are best at strengthening muscles and are easy on your joints. Stronger muscles help protect the joints by providing support and added stability.
Exercise also helps the joints absorb fluid and needed nutrients. |
Textbook of Natural Medicine 2nd Edition Volume 1Michael T. Murray, ND
See book keywords and concepts | | Similar, but not nearly as impressive, results in the treatment of atherosclerosis have been noted with chondroitin sulfate at a daily dose of 3 g (1 g with meals, three times daily).29
Liver extracts
Hydrolyzed liver extracts have been used to treat chronic liver diseases since 1896. Numerous scientific investigations into the therapeutic efficacy of liver extracts have demonstrated that these extracts improve fat utilization, promote tissue regeneration, and prevent damage to the liver. |
Ralph Golan, M.D.
See book keywords and concepts |  Find a multiple or a back/disc formula that provides most of these nutrients.
• Proteolytic (protein-digesting) enzymes can be used acutely for their anti-inflammatory effect (one or two capsules three or four times a day between meals and at bedtime).
• Try intramuscular injections of vitamin B-12 (1,000 micrograms a day for one to two weeks), with folic acid (2 or 3 milligrams) added in the syringe at least three times a week. After the initial two weeks, lessen the frequency of the injections to two or three injections a week for a month, then one to four injections a month as needed. |
Sheldon Saul Hendler and David Rorvik
See book keywords and concepts |  In another recent meta-analysis of nine randomized, controlled trials of glucosamine, glucosamine was significantly superior to placebo in seven of the studies and was superior to ibuprofen and equal to ibuprofen in the other two studies.
Recently, a long-term, randomized placebo-controlled trial of glucosamine sulfate's effects on osteoarthritis ended with the conclusion that the supplement halts progression of structural joint damage and reduces symptoms of those with osteoarthritis of the knee. |
Schuyler W. Lininger, Jr. DC
See book keywords and concepts |  One study found 60 mg per day of such supplements significantly lowered urinary oxalate levels in stone formers.77 Such a decrease should reduce the risk of stone formation. Are There Any Side Effects or Interactions? Refer to the individual supplement for information about any side effects or interactions.
Herbs That May Be Helpful
Highly trained practitioners of botanical medicine use several herbs to help facilitate passage of small kidney stones and to help prevent their formation.
The efficacy of these herbs has not been documented scientifically for people with kidney stones. |
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