Bill Sardi
See book keywords and concepts |
 Breast cancer and chondroitin
A remarkable study using oral chondroitin sulfate (a natural component of human connective tissue) in animals shows that breast tumors can be completely inhibited. Oral chondroitin sulfate has been shown to reduce the incidence and size of mammary tumors in virgin female mice. Chondroitin stimulates the production of HA.
Incidence of mammary tumors after 1 feeding
8 weeks of
Purified diet
35.0%
Purified diet +
0.5 % chondroitin sulfate
28.6%
1.0 % chondroitin sulfate
11.4%
2.5 % chondroitin sulfate
0. |
Mike Adams, the Health Ranger
See article keywords and concepts |
 Jonathan Wright, a doctor who educates other doctors about nutrition, wrote that men who are prone to prostate cancer should not take bovine sources of chondroitin sulfate. They can actually cause some problems.
When I read that, I thought, "I am not putting bovine chondroitin sulfate in my products." I went out and I searched and found sea cucumber. Sea cucumber has been used in Chinese medicine for thousands of years for dealing with joint problems and connective tissues -- it actually is a whole body tonic. It strengthens users in many ways. It is actually 20 percent chondroitin sulfate. |
| Some people will use chondroitin sulfate and they have these big arguments saying this is better, and that is better. Dr. Jonathan Wright, a doctor who educates other doctors about nutrition, wrote that men who are prone to prostate cancer should not take bovine sources of chondroitin sulfate. They can actually cause some problems.
When I read that, I thought, "I am not putting bovine chondroitin sulfate in my products." I went out and I searched and found sea cucumber. |
| It is actually 20 percent chondroitin sulfate. However, the chondroitins that are in there are different. The sugars that sit on them sit in different places, so it is a safer alternative.
Then we put the MSM in there because the MSM is a source of sulfur, which is needed in building those glycosaminoglycans, the connective tissues. MSM is also known to be a painkiller. You might find a lot of formulas with glucosamine, chondroitin sulfate, and MSM in them. They're foundational nutrients.
Now we go to the next level. You have inflammation in the joints. |
Jonathan V. Wright, M.D. and Alan R. Gaby, M.D.
See book keywords and concepts |
 Also, it is not known whether combination therapy is more effecrive than glucosamine or chondroitin sulfate alone. It is possible that chondroitin sulfate confers certain benefits that are not obtainable with glucosamine. We usually recommend glucosamine sulfate for our patients, without the addition of chondroitin sulfate. However, we have no objection if someone wants to use the more expensive combination treatment.
Vitamin E and Selenium
Vitamin E has a mild anti-inflammatory effect, similar to that of aspirin-like drugs. |
| In a 3-month, double-blind study, chondroitin sulfate (1,200 mg per day) was significantly more effective than a placebo at relieving the symptoms of osteoarthritis.10 Moreover, the benefits of chondroitin sulfate became more pronounced with time. In a separate 1-year, double-blind study of patients with osteoarthritis of the knee, supplementing with 800 mg per day of chondroitin sulfate significantly reduced pain, improved overall joint mobility, and appeared to slow the degenetation of joint cartilage. |
Jonny Bowden, Ph.D., C.N.S.
See book keywords and concepts |
 Well-absorbed and associated with only minor side effects, chondroitin sulfate can also decrease pain and slow the rate of cartilage loss in people with osteoarthritis. The Annual Scientific Meeting of the American College of Rheumatology in 2005 reported that the combination of glucosamine and chondroitin sulfate is at least as effective as the prescription drug cele-coxib (brand name Celebrex) in treating pain caused by moderate to severe osteoarthritis of the knee. So for best results, use them together. |
Mike Adams, the Health Ranger
See article keywords and concepts |
| When I read that, I thought, "I am not putting bovine chondroitin sulfate in my products." I went out and I searched and found sea cucumber. Sea cucumber has been used in Chinese medicine for thousands of years for dealing with joint problems and connective tissues -- it actually is a whole body tonic. It strengthens users in many ways. It is actually 20 percent chondroitin sulfate. However, the chondroitins that are in there are different. The sugars that sit on them sit in different places, so it is a safer alternative. |
Marshall Editions
See book keywords and concepts |
 Glucosamine sulfate works synergistically with chondroitin sulfate. Take 500 mg three times a day.
Herbs: Take 300 mg of boswellia three times a day to decrease inflammation and alleviate pain. Butterbur, which can be taken at 75 mg twice a day, has anti-inflammatory and antispasmodic effects. Ginger has been traditionally used for its anti-inflammatory effects and can help alleviate pain. Take 4 mg in two divided doses. Horsetail contains silica, which is excellent to help rebuild tissue. |
Jonny Bowden, Ph.D., C.N.S.
See book keywords and concepts |
| Those who are allergic to sulfates may take glucosamine hydrochloride and not glucosamine sulfate, and they should avoid chondroitin sulfate. Glucosamine is derived from shrimp, oyster, and crab shells, and chondroitin is derived from cartilage of cows, pigs, and sharks. There is no synthetically made glucosamine on the market.
Glucosamine and chondroitin help regrow cartilage. However, if you have no cartilage left, these nutrients will not do any good to o artificial knees. They may help, though, with 2 your other joints. |
Thomson Healthcare, Inc.
See book keywords and concepts |
 These results showed that glucosamine, either alone or in combination with chondroitin sulfate, did not effectively reduce pain in the overall group of subjects in this study (Clegg et al 2006).
Another group of investigators used a unique approach to study glucosamine's effects. Their randomized, double-blind trial enrolled 137 subjects with knee osteoarthritis who had been taking glucosamine for relief of painful symptoms and had experienced moderately beneficial results. Subjects were continued on an equivalent dose of glucosamine (n=71) or assigned to placebo (n=66). |
| A diminished growth rate, stimulation of hyaluronic acid, and increased chondroitin sulfate was seen after incorporation of the total triterpenic fraction of Centella asiadca into human embryonic fibroblasts (Del Vecchio et al, 1984).
Antineoplastic Effects: The fresh plant juice has moderate cytotoxic actions on human ascites tumor cells, but little, if any other antitumor effects (Jacker et al, 1982). Cytotoxic and antitumor effects of Centella asiatica involve direct action on DNA synthesis. The development of solid and ascites tumors was decreased by the herb (Babu, 1985). |
| Eighteen patients with the disorder who tested positive to the potassium stimulation test received 40 mL chondroitin sulfate 0.2% intravesically once weekly for 4 weeks and then once monthly for 1 year in an open-label study. Of the 13 patients followed for the entire 13-month study, 6 showed good response, 4 had partial response, 2 had fair response, and 1 patient had no response. Patients with epithelial permeability as demonstrated by the positive potassium challenge test may be more likely to respond to treatment with glucosaminogly-cans (Steinhoff et al 2002). |
Jonathan V. Wright, M.D. and Alan R. Gaby, M.D.
See book keywords and concepts |
| It is possible that chondroitin sulfate confers certain benefits that are not obtainable with glucosamine. We usually recommend glucosamine sulfate for our patients, without the addition of chondroitin sulfate. However, we have no objection if someone wants to use the more expensive combination treatment.
Vitamin E and Selenium
Vitamin E has a mild anti-inflammatory effect, similar to that of aspirin-like drugs. Although vitamin E is not nearly as strong as aspirin and related drugs, it also doesn't produce any of the side effects associated with these drugs. |
Thomson Healthcare, Inc.
See book keywords and concepts |
| One well-designed study cited in the analysis enrolled 1,583 patients with symptomatic knee pain and randomly distributed them across 5 treatment groups: glucosamine 1500 mg/day (n=317), chondroitin sulfate 1200 mg/day (n=318), glucosamine plus chondroitin (n=317), celocoxib 200 mg/day (n=318) and placebo (n=313). Investigators were looking for a 20% decrease in Western Ontario and MacMaster Universities Osteoarthritis Index (WOMAC) pain score from baseline to week 24. Compared with the high rate of response to placebo (60.1%), rates of response were just 3. |
| These results show that chondroitin sulfate, either alone or in combination with glucosamine, did not effectively reduce pain in the overall group of subjects studied (Clegg et al 2006).
An earlier meta-analysis of 15 randomized, placebo-controlled trials evaluated the structural and symptomatic efficacy of oral glucosamine or chondroitin in knee osteoarthritis. Glucosamine improved scores on all outcomes measures, including joint space narrowing. Chondroitin demonstrated improvement on two outcome measures: the Lequesne Index (e.g. |
| However, chondroitin sulfate did not modify disease progression, and the authors concluded there was no overall clinical significance in this trial. Patient assessment of pain and adverse effects were not evaluated (Rovetta et al 2002).
Combination therapy with glucosamine, chondroitin, and manganese ascorbate improved symptoms of knee arthritis but had equivocal effects on low-back arthritis in a 16-week, randomized, double-blind, placebo-controlled, cross-over pilot study involving 34 men from the United States Navy. |
James F. Balch, M.D. and Mark Stengler, N.D.
See book keywords and concepts |
 Chondroitin Sulfate
Description: chondroitin sulfate is a nutritional supplement extract made from cow's cartilage. It consists of glycosaminoglycans, substances that form cartilage. This supplement is mainly used for osteoarthritis.
Indications: Osteoarthritis Sprains/strains Precautions: Very high dosages may cause nausea. Dosage: The dosage used to treat osteoarthritis is 1,200 mg daily.
Colloidal Silver
Description: Colloidal silver refers to silver particles that are suspended in a water solution. |
Jonny Bowden, Ph.D., C.N.S.
See book keywords and concepts |
| Chondroitin sulfate is another building block of connective tissue. It actually stimulates the cartilage cells (called chondrocytes), and therefore works beautifully when paired with glucosamine to speed the regeneration and recovery of bone tissues. |
Marshall Editions
See book keywords and concepts |
| Usually it is combined with chondroitin sulfate. Take 1,500 mg daily of glucosamine with 1,200 mg of chondroitin. Methylsulfonylmethane (MSM) has natural anti-inflammatory benefits and contains the mineral sulfur, which can also be beneficial for shoulder pain. Take 4,000-8,000 mg daily. Take 4-6 g of fish oil a day to reduce inflammation and provide lubrication to the shoulder joints, but allow two to three months to see significant effects. If shoulder pain is linked to arthritis try taking 500 mg of niacinamide three times a day, as it has been clinically reported to help arthritic patients. |
Jonny Bowden, Ph.D., C.N.S.
See book keywords and concepts |
| The Annual Scientific Meeting of the American College of Rheumatology in 2005 reported that the combination of glucosamine and chondroitin sulfate is at least as effective as the prescription drug cele-coxib (brand name Celebrex) in treating pain caused by moderate to severe osteoarthritis of the knee. So for best results, use them together.
Glucosamine/chondroitin therapy requires patience: You may have to wait anywhere from eight to twelve weeks to see results. |
Marshall Editions
See book keywords and concepts |
| Glucosamine sulfate, which is usually combined with chondroitin sulfate, reduces knee pain and rebuilds cartilage. Take 1,500 mg of glucosamine daily with 1,200 mg of chondroitin. Take 4,000-8,000 mg of methylsulfonylmethane (MSM) a day for its I natural anti-inflammatory benefits. Niacinamide has been clinically reported to help arthritis, which can present as knee pain. Take 500 mg three times a day. Higher doses should be supervised by a doctor. |
| Glucosamine sulfate, which is usually combined with chondroitin sulfate, reduces leg pain and rebuilds cartilage. Take 1,500 mg of glucosamine daily with 1,200 mg of chondroitin. Take 4,000-8,000 mg of methylsulfonylmethane (MSM) a day for its natural anti-inflammatory benefits. Taking 4-6 g of fish oil a day also reduces inflammation, but allow two to three months to see significant effects. Niacinamide has been clinically reported to help arthritis, which can present as leg pain. Take 500 mg three times a day. Higher doses should be supervised by a doctor. |
| Glucosamine sulfate, which is usually combined with chondroitin sulfate, reduces joint pain and rebuilds cartilage. Take 1,500 mg daily of glucosamine with 1,200 mg of chondroitin. Methylsulfonylmethane (MSM) has natural anti-inflammatory benefits and contains the mineral sulfur, which is an important component of cartilage. Take 4,000-8,000 mg daily.
Herbs: Take 500 mg of bromelain three times a day for its natural anti-inflammatory effects. Cayenne cream can help to inhibit the transmission of pain messages to the brain. Apply the cream directly to the affected area two to four times a day. |
| Usually it is combined with chondroitin sulfate. Take 1,500 mg daily of glucosamine with 1,200 mg of chondroitin. Methylsulfonylmethane (MSM) has natural anti-inflammatory benefits and contains the mineral sulfur, an important component of cartilage. Take 4,000-8,000 mg daily. Take 500 mg of niacinamide, which has been reported to help arthritic patients, three times a day. Higher dosages should be supervised by a doctor. Take 250 mg of sulfur four times a day as it is important for cartilage structure. Vitamin C is beneficial in collagen synthesis repair, a major component of bone. |
Bottom Line Health
See book keywords and concepts |
| Glucosamine sulfate, derived from crab, lobster or shrimp shells, and chondroitin sulfate, usually derived from shark cartilage, can be taken separately or together to supply the nutritional building blocks that are needed for new cartilage.
Typical dose: 1,500 mg daily, which often can be reduced to 500 mg when symptoms improve.
Important: It can take six to eight weeks for glucosamine and chondroitin to take full effect.
AT-HOME PHYSICAL THERAPY
In addition to taking natural painkillers, try these therapies...
•Hot/cold therapy. |
Mike Adams, the Health Ranger
See article keywords and concepts |
 It is like chondroitin sulfate. People said, "No, you never get any in." Maybe you do get two or three percent in. You certainly do not get, from a biochemical point of view, enough to make a big difference. It is probably that the body breaks it down to precursors then you can use those for rebuilding in the body. I think it is probably similar to that kind of process.
The other thing is, there are co-factors. He did three experiments. He just did B-complex and he did not see much. There was a little bit. Then he just did the RNA with the sardines or the yeast RNA, and he got good results. |
Mark Sircus
See book keywords and concepts |
 Between 2000 and the present, FDA prohibits companies that sell glucosamine and chondroitin sulfate from telling Americans that those dietary ingredients treat osteoarthritis and relieve osteoarthritic pain and stiffness. Approximately 20 million Americans suffer needlessly from osteoarthritis.
6 lllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllll
Since ending one s life with cancer is not pleasant it behooves all of us to be concerned with its prevention.
""1 WT" t certainly is time to get serious about cancer prevention, with the disease predicted to surge in the next 15 years. |
Mike Adams, the Health Ranger
See article keywords and concepts |
| You might find a lot of formulas with glucosamine, chondroitin sulfate, and MSM in them. They're foundational nutrients.
Now we go to the next level. You have inflammation in the joints. You need to knock that inflammation down. The nutrients we just talked about slowly rebuild and repair connective tissues over the course of weeks or months. We put other nutrients in Joint Health Formula that act much more quickly, like tumeric and quercetin chalcone.
If you have inflammation, you have pain. |
Email this page to a friend
