Jack Challem
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 University of Swansea, Wales, asked 127 students to take daily high-potency multivitamins (with amounts about ten times higher than Centrum or One-A-Day) or placebos for one year. After just three months, women taking the multivitamins reported that their moods had substantially improved. These improvements continued throughout the study, and by its end, women taking vitamins reported that they felt more composed, more "agreeable," and in better mental health. Their thinking processes were sharper as well. Men in the study also reported feeling better and more agreeable. |
| Multivitamins
Principal use: To reverse moodiness, irritability, impatience, anger, and depression. multivitamins are a good all-round mood and mind enhancer.
What else you should know. A high-potency multivitamin (described in the previous section) can have a powerful and positive effect on mood—even if you think you are already even-tempered and normal. This type of supplement will contain most or all of the B-complex vitamins, as well as vitamins C and E and a few other nutrients. It's an ideal supplement for someone who does not want to, or need to, take a lot of capsules or tablets. |
Marshall Editions
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 Pregnant women should take a specially formulated multivitamin, following the instructions on the label. Some multivitamins can cause nausea, and you may need to switch brands, take it at a different time, or take it with food. Studies have shown that vitamin B6, taken at 30 mg twice a day, can also help with nausea. Take 500-1,000 mg of activated charcoal a day to
405 absorb toxins in the digestive tract. This is helpful if you have been exposed to microorganisms from food or water. |
J. Douglas Bremner
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 In fact, women who might get pregnant should not take multivitamins that have any vitamin A or beta-carotene in them even at lower doses, given their known association with birth defects. The average woman already gets 120% of required vitamin A from diet alone, so there is no need for supplementation. For men who eat a balanced diet that includes fruits and vegetables, there is no need for vitamin A supplementation.
Based on these studies, doctors such as Dr. |
Thomson Healthcare, Inc.
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 The 2006 meta-analysis by Goh and colleagues also showed that supplementation with folic acid-fortified multivitamins protects against neural tube defects (Goh et al 2006). For each study included in the analysis, odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. Among the eight case-control studies and 11 cohort and randomized, controlled trials included, women beginning supplementation prior to conception and taking it through the first trimester were consistently protected against neural tube defects (OR 0.67, 95% CI 0.58-0.77 in case-control studies; OR 0.52, 95% CI 0. |
| Cancer Prevention
Prostate Cancer
Heavy use of multivitamins, including beta-carotene, may increase the risk of advanced and fatal prostate cancer, according to an article in the Journal of the National Cancer Institute. Investigators involved in the National Institutes of Health—AARP Diet and Health Study screened men (n=295,344) at entry for self-reported multivitamin use and followed them for 5 years; 47% of subjects reported taking beta-carotene supplements more than 7 times per week, compared with 20% who reported never taking beta-carotene. |
| The preparation also included multivitamins and trace elements. Hepatoprotective effects have been observed for various ginsenosides. Hepatotoxicity was reduced in cultured rat hepatocytes by administration of ginsenosides (Nakagawa et al, 1985; Hikino et al, 1985). Higher doses of various ginsenosides in both series actually produced cytotoxic actions (Tsang et al, 1986). In another study, Ginseng was administered orally to hepatotoxic rats. |
Ray D. Strand
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 Interestingly, recent studies reported in the New England Journal of Medicine have shown that 93 percent of the people in Boston are deficient in vitamin D—even those taking multivitamins.14 Other studies are now revealing that the RDA of vitamin D is too low (200 IU) and patients need to take 500-800 IU of vitamin D, which is again an optimal level. This dosage is still considered to be well within a safe range.15
Niacin (Vitamin B3)
High doses of niacin supplementation may create flushing to the skin, nausea, and liver damage. |
| Taking a daily multivitamin cannot protect you from degenerative disease either. multivitamins are primarily based on RDAs. It is rare to see any reference in the medical literature to a health benefit in patients who are simply taking a mvrltivitarnin. You must take significant amounts of high-quality antioxidants and minerals if you have any desire to prevent or slow down the chronic degenerative diseases described in this book.
The obvious next question should be, Is it safe to take these supplements at these optimal levels? |
Thomson Healthcare, Inc.
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| A significant reduction in risk for first-time occurrence of neural tube defects was observed in 18,508 pregnant women consuming folic acid-containing multivitamins compared to no folic acid consumption (Milunsky et al 1989). Similar results were reported in another study (Czeizel et al 1992).
Ulcerative Colitis and Colonic Adenomas
Folate supplementation can reduce cell abnormalities in the rectal mucosa of patients with ulcerative colitis. Folic acid 15 mg/day (as calcium folate) or a placebo was taken (double-blind) for 3 months by 24 patients with UC of more than 7 years' duration. |
Mark Sircus
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 All of these findings should lead our doctors to the conclusion that magnesium should be increased in CF, yet we find that only multivitamins are suggested with low magnesium content.
The Emerging Truth
Magnesium, Metabolic Syndrome, and Diabetes
The rising concern about metabolic syndrome26 (synonymous with pre-diabetes) is another concern increasing today, and magnesium's role simply cannot be ignored in these disorders, but it is! |
Mike Adams, the Health Ranger
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 Oh yeah, and one more thing: Don't send me multivitamins made with cyanocobalamin. I know I've recommended products in the past made with that synthetic form of vitamin B-12, but I've learned more since then and I no longer recommend any supplements made with cyanocobalamin. (Get products like Ola Loa instead, at www.DrinkYourVitamins.com )
Who I'm about to recommend
By the way, I'm about to make big recommendations for some companies I'm seriously impressed with. These companies are:
Dragon Herbs (www.DragonHerbs.com)
Incredibly high-quality Chinese Medicine herbs. |
Mike Adams, the Health Ranger
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 It's also got multivitamins, herbs, antioxidants, and minerals. That is an all-in-one. You can live on that.
The primary difference between the Super Greens and the Super Berry is that one has vegetable greens and the other has berries. So they are slightly different. The Super Berry is sweetened with tagatose, as well as xylitol, fructooligosaccharides, and a little stevia. In the Super Greens, we have mannitol, xylitol, fructooligosaccharides, and a little stevia. These are' the basic differences.
Mike: That is the only ingredient I would ever be concerned about. |
Bottom Line Health
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| It's important that all women of child-bearing age follow the advice about multivitamins and folic acid because many pregnancies are unplanned, Dolan says.
.-Q To learn more about folic acid, visit the Centers for Disease Control and Prevention Web site at www.cdc.gov/ncbddd/folicacid.
Diabetes Drug May Boost Fertility
The drug metformin (Glucophage), which is used to make the tissues of diabetics more insulin-sensitive, can help treat the type of infertility that is caused by a failure to ovulate.
In some women who are not diabetic, excess insulin levels interfere with ovulation. |
| Any brand of a single vitamin, such as vitamin C, is usually fine, but the potency varies among brands of multivitamins. Some less expensive brands, such as Wal-Mart's Spring Valley, are well-made, but some supermarket and drugstore brands may not be as reliable.
Name brands that are made by divisions of major pharmaceutical companies usually deliver what they claim.
Examples: Centrum and One-A-Day.
Tod Cooperman, MD, president of ConsumerLab.com, a consumer product watchdog organization, White Plains, NY. |
Hyla Cass, M.D.
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 This dose is fine to take in addition to the tocopherol form of vitamin E that's usually found in multivitamins.
D-Ribose
While we're on the topic of heart health, I'd like to introduce one of my favorite supplements, D-ribose. It works by helping your heart cells to produce energy. Just think of it: your heart muscle is beating at least sixty times a minute, twenty-four hours a day, three hundred sixty-five days a year. It never rests! So it has to be supplied with a continuous and reliable source of fuel. |
Stacy Malkan
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 Ames zipped through a series of complicated slides about cellular cytoplasm and mitochondrial matrix and then got straight to the point: we're living longer, there's no need to worry about parts per billion of pesticides, the real problem is poor diets and micronutrient deficiencies (and by the way he has a company that sells multivitamins and mineral pills). He is most concerned about Vitamin D deficiencies. According to Dr. |
Mike Adams, the Health Ranger
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 We have multivitamins for small pets and large pets.
One of the interesting things about designing for animals is they range from 5 pounds up to 200 pounds. You have to be able to have one or two products that supply that entire size range. The Small Pet Mighty-Multi you can break in half for easy dosing, and you can give half a one a day or more. The Large Pet Mighty-Multi you can also break in half, or you can give three or four a day.
We try to cover the complete range of nutrients that animals require. |
Bill Sardi
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 In a study of postmenopausal women, among the 54% who took multivitamins, 78% were found to have unmetabolized folic acid in their blood serum and experienced about a 23% reduction in natural killer cell activity. [Journal Nutrition 136: 1 89-94, 2006] Health authorities are concerned that this may cause symptomless, undetected micrometastatic cancer to begin to grow and spread. |
| In a study of postmenopausal women, 54% of whom who took multivitamins, 78% had unmetabolized folic acid in their blood serum and experienced about a 23% reduction in natural killer cell activity. [Journal Nutrition 136: 189-94, 2006] Health authorities are concerned that this may cause symptomless, undetected micrometastatic cancer to begin to spread and become deadly. |
| Cancer Causes Control 12: 927-34, 2001] There was a sharp unexplained decline in colon/rectal cancer incidence in the late 1980s, which could be explained by the increase in folic acid in multivitamins in the 1970s. [Journal National Cancer Institute 86: 997-1006, 1994] This benefit would have only gone to the users of dietary supplements.
Modest changes in folic acid intake, within the range of what is considered normal, can have a significant impact upon colon cancer risk. |
| The vitamin D Council now suggests 2,000 IU per day, which is five times greater than most multivitamins provide .
Vitamin D supplementation should be mandated for human populations of blacks, those living in northern latitudes, smokers, over-consumers of alcohol, and all other high-risk groups for colon cancer.
Patients will likely ask their physicians about the potential for vitamin D overdose and are likely to receive mistaken advice. Most physicians have been trained that high-dose vitamin D causes excessive buildup of calcium in cells. |
| The gamma form of vitamin E tocopherols is not commonly provided in multivitamins. [Journal National Cancer Institute 92: 2018-23, 2000]
Supplementation with up to 200 IU of d-alpha tocopherol, the natural form of vitamin E from soy, along with ample amounts of gamma tocopherol and mixed tocotrienols appears to be wise for adult males. |
Caldwell B. Esselstyn, Jr., M.D.
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 Multivitamins. I suggest one a day to make certain that you are covering basic requirements.
2. Vitamin BI2.1 favor 1,000 meg (micrograms) daily.
3. Calcium. People over age fifty should take 1,000 milligrams a day. People over age sixty should take 1,200 milligrams a day.
4. Vitamin D}. Those over 50 should take 1,000 IU (International Units of vitamin D3) a day.
5. Omega-3 fatty acids. You can fulfill your daily requirement by consuming one tablespoon of flaxseed meal each day—perhaps sprinkling it over cereal. Be sure to refrigerate ground flaxseed.
6. Cholesterol-lowering drugs. |
Jonny Bowden, Ph.D., C.N.S.
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 In addition, most multivitamins have at least 400 meg of folic acid, though Fd like to see more in everyone's diet.
Don't forget that B vitamins work best when they work together. Folic acid is, after all, a B vitamin and it needs its partners—B12 and B6— to effectively carry out its functions. You can easily take extra folic acid (as in an additional supplement), but be sure to get a foundation of the other Bs, either in a B complex or multiple vitamin. |
Jack Challem
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 The Value of Nutrient Testing
Ideally, people should be tested to determine the nutrient levels in their bodies before they take high doses of individual supplements— that is, doses beyond those found in high-potency multivitamins. At the Center for the Improvement of Human Functioning International, a government-certified, on-site testing laboratory has measured people's nutrient levels for more than thirty years.
Each patient who comes to the center undergoes blood tests to assess his or her nutrient levels and also is given more conventional medical tests. |
Craig Pepin-Donat
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 In 1976, the Proxmire Vitamin Mineral Amendment removed the FDA's ability to regulate potency limits, classify a vitamin or mineral as a drug based on its potency or limit the marketing of multivitamins. Then, in 1994, the Dietary Supplement Health and Education Act (DSHEA) expanded the meaning of dietary supplements to include "a vitamin or mineral, an herb or other botanical, an amino acid, a dietary substance for use by man to supplement the diet by increasing the total dietary intake, or a concentrate, metabolite, constituent, extract, or combination of the preceding ingredients. |
Hyla Cass, M.D.
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| In one revealing study, only 17 percent of diabetics who took multivitamins reported having an infection—such as a cold, the flu, or a stomach flu—while 93 percent who took a placebo (dummy) pill did report having one. This same study found that 89 percent of diabetics who took the dummy pill missed at least one day of work during the one-year study, while none of the multivitamin users missed work in that time period! This sounds like cheap and simple enough insurance! (To read more, see www.diabetesincontrol.com/ modules.php?name=News&file=article&sid= 10070. |
| We are also supplying 3,000 seniors who are at risk for malnutrition with multivitamins, and we get wonderful letters all the time, thanking us for the difference our vitamins have made in their health and well-being (www.nourishamerica.org).
Even if your diet is perfect, the world you live in isn't. We're surrounded by toxins and pollutants, some of which we take in through our food. We need extra nutrient protection to help guard against the harm they can do. Most of us have stressful, busy lives, which means higher nutrient requirements. And—let's face it—who has a perfect diet? |
Jack Challem
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| You should also have clear objectives when you move beyond multivitamins and multiminerals. For example, one might be to reduce your blood-sugar levels. Finally, remember that supplements work best if they accompany a healthy diet and are not used as an antidote for eating too many junk foods.
Creating a Sound Supplement Program
We would like you to take a high-potency multivitamin supplement as a foundation, which you can build on with other supplements. By "high potency," we mean a supplement containing 20 to 50 mg each of vitamins Bl, B2, B3, and B6. |
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